Across our own region, the picture is especially worrying. In Papua New Guinea – where TB and drug-resistant TB rates are among the highest in the world – the country still lacks a reference laboratory for diagnosing drug-resistant TB and relies on Australia for technical support. In the Philippines, HIV infections have skyrocketed from around 4,400 in 2010 to nearly 30,000 in 2024. Meanwhile, the loss of US funding has hollowed out TB surveillance and drug-resistant TB management, leaving major gaps in care regionally.
The reality of infectious diseases is that, when left unchecked, they worsen and spread. Cutting funding risks reversing years of hard-won progress. Millions now live healthily with HIV thanks to viral suppression, yet HIV still causes more than 600,000 deaths each year. Community-based organisations supported by the Global Fund are among the most effective at improving prevention and treatment outcomes. Their progress must not be undone.
In March this year, the WHO Western Pacific office warned that the loss of US funding is already undermining programs. In Cambodia and the Philippines, national TB plans are being delayed, HIV and hepatitis services in Laos and Cambodia risk losing core staff, and malaria surveillance and drug-resistance monitoring across the Mekong region have been slashed. In PNG, where TB and malaria remain rampant, mass drug administration campaigns face cancellation. These are not one-off program cuts, they are the start of a multi-year decline in Global Fund resources, and they directly weaken the capacity of our neighbours to manage infectious diseases and contain their spread.
At the same time, medical advances show extraordinary potential. New injectable pre-exposure prophylaxis (PrEP) can prevent HIV acquisition and protect people at high risk, lowering transmission more broadly. Tuberculosis, which still causes 1.5 million deaths each year, can now be detected earlier and treated with shorter, safer regimens – innovations that Australia helped pioneer through its funding of the TB Alliance. These breakthroughs can only be scaled with sustained investment.
Australia has also contributed to global TB innovation. Funding to the TB Alliance helped develop Pretomanid, a drug now central to shorter regimens for drug-resistant TB. Today, Australian-supported programs are helping roll out these regimens in PNG, Mongolia, Brazil and the Philippines. This is a success story: Australian taxpayer dollars, MSF clinical trials, WHO technical assistance and Global Fund financing combining to deliver safer cures for patients who once faced years of toxic treatment.
With the collapse of US government funding, the idea that governments in developing countries and fragile states can fill these global health funding gaps themselves and cover their own needs is not viable. As our recent report Deadly Gaps shows, the cost burden inevitably falls on patients who cannot afford care.
Fighting HIV, tuberculosis and malaria is a global, generational challenge, and it is far from over. Australia may need to carry a larger part of the global health funding burden to keep us and our neighbours safe and well. Beyond funding, Australia’s moral leadership will be increasingly important in persuading other states to maintain and strengthen efficient and effective multilateral approaches to global health challenges.